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2024, Cilt 54, Sayı 1, Sayfa(lar) 049-056 |
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Hepatitis A Virus Seropositivity in Young Individuals: Five-Year Retrospective Evaluation |
Pelin Özmen1, Nazife Akman2, Zeynep Akıdağı2, Selma Gökahmetoğlu3 |
1Nevşehir Hacı Bektaş Veli Üniversitesi, Diş Hekimliği Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Nevşehir, Türkiye 2Kapadokya Üniversitesi, Kapadokya Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümü, Nevşehir, Türkiye 3Erciyes Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Kayseri, Türkiye |
Keywords: Hepatitis A virus, health intern, seropositivity, HAV IgG, HAV IgM |
Objective: Hepatitis A Virus (HAV) is one of the important factors of acute viral hepatitis that can be transmitted
from person to person by direct contact or fecal-oral route. Although HAV seroprevalence varies in different
sociodemographic layers, healthcare workers are in the risk group under all circumstances. The aim of this study
is to conduct a five-year retrospective evaluation of HAV seropositivity in health trainees who were excluded in
routine anti-HAV vaccination.
Methods: The HAV IgM and HAV IgG data of 733 students were included in the study. Serological rates with values below 1.0 Signal/Cut-off (S/CO) were considered ‘non-reactive’, the ones with S/CO values ≥1.0 were considered ‘reactive’. SPSS Ver.21 program was used in the statistical analysis of the data; the relationship between categorical variables was determined by the chi-square test and p<0.001 was considered significant. Results: Anti-HAV IgM values were found to be negative in all students. The rate of seropositive students was 20% (n=147), while 2019 was found to be the year with the highest positivity rate (26.9%). The seropositivity rates of female and male students were 57.8% (85/147) and 42% (62/147), respectively, which indicated a significant increase for female sex (p<0.001). In conclusion, HAV seropositivity was found to be low in the present study. Healthcare professionals should be vaccinated against HAV infection, due to occupational exposure risks. |
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